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The use of anti-DM1/DM4 antibodies in pharmacokinetic (PK) studies is crucial for understanding the behavior of Antibody-Drug Conjugates (ADCs) that utilize DM1 or DM4 as their cytotoxic payloads. DM1 (maytansinoid DM1) and DM4 (maytansinoid DM4) are potent microtubule inhibitors used in ADCs to ...
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