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benzodiazepines only bind to one of the five receptors the a subunit which just affects memory also non benzodiazepines are relatively short acting with half-lives ringing from ultra short of one hour to intermediate to six to nine hours this prevents the dangers of sleepiness during the day many people turn to end a histamines and perceived less intense sleeping aid but there's little evidence that they improve sleep they can also cause next day sedation that impairs driving as well as racing heartbeat and constipation the medical letter which reviews drugs recommends against using hand esta means for sleep some doctors say uses users of Tylenol PM may be taking acetaminophen they do not need which can cause liver failure how much you're sleeping pulse actu Ambisom ally help that's a great question Liam in an analysis done by the National Institute of Health the researchers concluded that although ambien lunesta and Sonata worked the results were not overwhelming the analysis said that the average time to