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Ativan is an anti-anxiety medication most effectively used in tandem with therapy. It is one of the safest and most effective tranquilizers, and works by inducing a calming and soothing sensation on the mind. This effect has been shown to reduce symptoms of Generalized Anxiety Disorder (GAD) like excessive anxiety, excessive worry, restlessness, fatigue from anxiety, difficulty concentrating, irritability, muscle tension, and sleep disturbances from anxiety.