Papillomaviruses (PVs) consist of small, nonenveloped, icosahedral DNA viruses, which can infect a wide range of species from fish to reptiles, birds and vertebrates, as well as humans. Human papillomaviruses (HPVs) are strongly correlated with various human cancers, in particular, cervical cancer and head and neck cancer. As a result, there is a great need for animal model systems that accurately mimic PV infections in humans.
