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The involving glycerol needed is entirely dependent on body weight. For people weighing 125 lbs, 25 to 30 ml is sufficient. For 125 to 200 lbs, 50 ml and for 200 and above lbs, 75 ml is needed. As far as restrictions are concerned, none been recently registered so far which is why it has been fda approved. Glycerol has hydrating benefits as well as its potential muscle enhancing properties makes it a powerful tool for the athletes.