Comfort Suites St Charles-St Louis
Welcome to Comfort Suites St Charles-St Louis, where you’ll feel at home for as long as you need to stay. Our convenient, affordable hotel in St Charles, Missouri is waiting for you just off I-70 at South Main Street along the shores of the Missouri River. Stay in comfort with us when you want to be close to Ameristar Casino, downtown St. Louis and much more.
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